From "Abyss"

Discoveries from the Abyss: The Abyssomicins and Their Total Synthesis.

Abyssomicin C is a recently discovered antibiotic with promising antibacterial activity, high structural complexity, and a novel mechanism of action. We give an account of our abyssomicin campaign and some of the discoveries that were borne of our total synthesis efforts, including a new Lewis acid-templated Diels-Alder reaction, the previously undescribed atrop-abyssomicin C, a facile Brønsted...

Eukaryotic Richness in the Abyss: Insights from Pyrotag Sequencing

BACKGROUND The deep sea floor is considered one of the most diverse ecosystems on Earth. Recent environmental DNA surveys based on clone libraries of rRNA genes confirm this observation and reveal a high diversity of eukaryotes present in deep-sea sediment samples. However, environmental clone-library surveys yield only a modest number of sequences with which to evaluate the diversity of abyssa...

A new vision of the Earth from the Abyss

AbYSS: Adapting Scatter Search for Multiobjective Optimization

In this paper we propose a new algorithm for solving multiobjective optimization problems. Our proposal adapts the well-known scatter search template for single objective optimization to the multiobjective domain. The result is a hybrid metaheuristic algorithm called AbYSS, which follows the scatter search structure but using mutation and crossover operators coming from the field of evolutionar...

Plumbing the Abyss: Black Ring Microstates

We construct the first smooth, horizonless “microstate geometries” that have the same charges, dipole charges and angular momenta as a BPS black ring whose horizon is macroscopic. These solutions have exactly the same geometry as black rings, except that the usual infinite throat is smoothly capped off at a very large depth. If the solutions preserve a U(1)×U(1) isometry, then this depth is lim...